Atlas-based assessment of vascular territories on brain MR images of stroke patients

On brain MR images, stroke lesions coalesce with other manifestations of white matter disease and inflammation producing the same signal change. Dedicated special MR sequences only allow to distinguish 60% of the strokes during a short period of time after they occur. This makes difficult to locate and delineate stroke lesions and consequently leads to erroneous prognosis, incorrect estimation about the extent of the damage caused by the stroke and may lead to false diagnosis. Brain atlases of the vascular territories of each main artery have been developed previously. With this project we aim to apply them to MR images of stroke patients and, using a multimodality approach developed in-house, validate their applicability to clinical research on stroke or evaluate modifications and alternatives for further developments.