MRS funding – creating excellent science.

You can read about it in these publications.

Daniel Baillache PhD Student - 2020

Pyrazolopyrimidine Library Screening in Glioma Cells Discovers Highly Potent Antiproliferative Leads That Target the PI3K/mTOR Pathway, 2020, Bioorganic and Medicinal Chemistry, 28 (1), 115214. Valero T, Baillache DJ, Fraser C, Myers SH, Unciti-Broceta, A. DOI: 10.1016/j.bmc.2019.115215 Link to publication

Julian Schwartze PhD Student - 2019

TGF-β in Vascular Pathobiology, 2019, Schwartze J. Chapter in the “Textbook of Vascular Medicine". Springer Nature Switzerland AG. Touyz R, Delle C (Eds) DOI: 10.1007/978-3-030-16481-2_13 Link to publication

Aryan Baghbadrani PhD Student - 2019

Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart, 2019, Nature Communications 10(1):5173. Taylor JM, Nelson CJ, Bruton FA, Baghbadrani AK, Buckley C, Tucker CS, Rossi AG, Mullins JJ, Denvir MA. DOI: 10.1038/s41467-019-13112-6 Link to publication

Faidon Kyriakou PhD Student - 2019

Evaluation of a new approach for modelling full ring stent bundles with the inclusion of manufacturing strains, 2019, Annals of Biomedical Engineering p13. Kyriakou F, Bow D, Dempster W, Brodie R & Nash D. DOI: 10.1007/s10439-019-02322-0 Link to publication

Elizabeth Hay PhD Student - 2019

Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid-1 receptor gene promoter; implications for cannabinoid pharmacogenetics, 2019, Hum Mutat Oct 14. Hay EA, Cowie P, McEwan AR, Ross R, Pertwee RG, MacKenzie A. doi: 10.1002/humu.23931 Link to publication

Elizabeth Hay PhD Student - 2019

Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour, 2019, Psychoneuroendocrinology 109:104407. Hay EA, McEwan A, Wilson D, Barrett P, D'Agostino G, Pertwee RG, MacKenzie A. DOI: 10.1016/j.psyneuen.2019.104407 Link to publication

Kym Bain PhD Student - 2019

Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity, 2019, Br J Dermatol. Apr 13. Bain KA, McDonald E, Moffat F, Tutino, M, Castelino M, Barton A, Cavanagh J, Ijaz UZ, Siebert S, McInnes IB, Astrand A, Holmes S, Milling SWF. DOI: 10.1111/bjd.18008 Link to publication

Sam Benson PhD Student - 2019

SCOTfluors: small, conjugatable, orthogonal and tunable fluorophores for in vivo imaging of cell metabolism, 2019, Angew Chem Int Ed 58, 6911-6915. Benson S, Frnandez A, Barth N et al. DOI: 10.1002/anie.201900465 Link to publication

Ines Nearchou PhD Student - 2019

Novel Internationally Verified Method Reports Desmoplastic Reaction as the Most Significant Prognostic Feature For Disease-specific Survival in Stage II Colorectal Cancer, 2019, American Journal of Surgical Pathology, 43(9):1239-1248. Nearchou IP, Kajiwara Y, Mochizuki S, Harrison D, Caie P, Ueno H. DOI: 10.1097/PAS.0000000000001304 Link to publication

Tiberiu Pana Vacation Scholar - 2019

Individual and Combined Impact of Heart Failure and Atrial Fibrillation on Ischemic Stroke Outcomes A Prospective Hospital Register Cohort Study, 2019, Stroke Vol 50, No 7. Pama TA, McLernon DJ, Mamas MA, Bettencourt-Silva JH, Metcalf AK, Potter JF, Myint PK. DOI: 10.1161/STROKEAHA.119.025481 Link to publication

George McCanney PhD Student - 2019

Low sulfated heparins target multiple proteins for central nervous system repair, 2019, Glia, 67, 4, pp668-687. McCanney GA, McGrath MA, Otto TD, Burchmore R, Yates EA, Bavington CD, Willison HJ, Turnbull JE, Barnett SC. DOI: Link to publication

Kirstyn Gardner Vacation Scholar - 2019

Cortical thickness, white matter hyperintensities, and cognition after stroke, 2019, International Journal of Stroke, April. Dickie DA, Gardner K, Wagener A, Wyss A, Arba F, Wardlaw JM, Dawson J. DOI: Link to publication

Elizabeth Hay PhD Student - 2019

Genetic and pharmacological influences modulating tissue specific regulation of the cannabinoid receptor-1 gene promoter implications for cannabinoid pharmacogenetics, 2019, BioRxiv. Hay E, Cowie P, McEwan A, Wilson D, Ross R, Barrett P, Pertwee RG, MacKenzie A. DOI: Link to publication

Elizabeth Hay PhD Student - 2019

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests its role in anxiety and male alcohol intake, 2019, BioRxiv. McEwan A, Hay E, Davidson C, Turnbull Y, Marini P, Wilson D, McIntosh A, Adams MJ, Murgatroyd C, Barrett P, Delibegovic M, Clark, T, MacKenzie A. DOI: Link to publication

Maria Gómez-Herranz PhD Student - 2019

The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis, 2019, Cellular Signalling, Aug, 60, pp39-56. Gómez-Herranz M, Nekulova M, Faktor J, Hernychova L, Kote S, Sinclair EH, Nenutil R, Vojtesek B, Ball KL, Hupp TR. DOI: 10.1016/j.cellsig.2019.03.024 Link to publication

Awa Sarr PhD Student - 2019

Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031, 2019, Scientific Reports, 9, 7643. Sarr A, Bre J, Um I, Chan T, Mullen P, Harrison DJ, Reynolds PA. DOI: 10.1038/s41598-019-44089-3 Link to publication

Ines Nearchou PhD Student - 2019

Automated Analysis of Lymphocytic Infiltration, Tumor Budding, and Their Spatial Relationship Improves Prognostic Accuracy in Colorectal Cancer, 2019, Cancer Immunology Research, 7(4), pp.609-620. Nearchou IP, Lillard K, Gavriel CG, Ueno H, Harrison DJ, Caie PD. DOI: 10.1158/2326-6066.CIR-18-0377 Link to publication

Roopam Gupta PhD Student - 2019

Label-free optical hemogram of granulocytes enhanced by artificial neural networks, 2019, Optics Express 27, 13706-13720. Gupta R, Chen M, Malcolm GPA, Hempler N, Dholakia K, Powis S. DOI: Link to publication

Kyriakos Michail PhD Student - 2019

An in vitro model for studying CNS white matter, 2019, F1000 Research. Bijland S, Thomson G, Euston M, Michail K, Thümmler K, Mücklisch S, Crawford CL, Barnett S, McLaughlin M, Anderson J, Linington C, Brown E, Kalkman ER, Edgar J. DOI: Link to publication

Elizabeth Hay PhD Student - 2018

Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4, 2018, Nutritional Neuroscience. July. Sergi D, Morris AC, Kahn DE., McLean, FH, Hay EA, Kubitz P, MacKenzie A, Martinoli MG, Drew JE, Williams LM. DOI: 10.1080/1028415X.2018.1501533 Link to publication

Sarah McGrath PhD Student - 2018

Protease-activated receptor-2 in synovial joint pathobiology, 2018, Frontiers in Endocrinology, 9, p.257. McCulloch K, McGrath S, Huesa C, Dunning L, Litherland G, Crilly A, Hultin L, Ferrell WR Lockhart JC, Goodyear CS. DOI: 10.3389/fendo.2018.0025 Link to publication

Caroline Busch PhD Student - 2018

Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal, 2018, Cell Death & Disease. Volume 9, Article number: 927. Toofan P, Busch C, Morrison H, O'Brien S, Jørgensen H, Copland M, Wheadon H. DOI: 10.1038/s41419-018-0905-2 Link to publication

Ieva Keraite PhD Student - 2018

Laser ablation of polylactic acid sheets for the rapid prototyping of sustainable, single-use, disposable medical micro-components, 2018, ACS Sustainable Chemistry & Engineering 6: 4: 4899–4908. Alfredo Edoardo Ongaro, Keraite I, Liga A, Conoscenti G, Coles S, Schulze H, Bachmann TT, Parvez K, Casiraghi C, Howarth NM, La Carrubba V, Kersaudy-Kerhoas M. DOI: 10.1021/acssuschemeng.7b04348 Link to publication

Ieva Keraite PhD Student - 2018

A simple and robust real-time qPCR method for the detection of PIK3CA mutations, 2018, Scientific Reports 8: 4290. Alvarez-Garcia V, Bartos C, Keraite I, Trivedi U, Brennan PM, Kersaudy-Kerhoas M, Gharbi K, Oikonomidou O, Leslie NR. DOI: 10.1038/s41598-018-22473-9 Link to publication

Andrew Ablett Vacation Scholar - 2018

Cognitive impairment is associated with mortality in older adults in the emergency surgical setting: Findings from the Older Persons Surgical Outcomes Collaboration (OPSOC): A prospective cohort study, 2018, Surgery, 165, 5, p978–984 . Ablett A, McCarthy K, Carter B, Pearce L, Stechman M, Moug M, Hewitt J, Myint PK, Older Persons Surgical Outcomes Collaboration DOI: 10.1016/j.surg.2018.10.013 Link to publication

Theresa Mulholland PhD Student - 2018

Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient, 2018, Nature Scientific Reports 8: 14672. Mulholland T, McAllister M. DOI: 10.1038/s41598-018-33055-0 Link to publication

Jihan Anderson PhD Student - 2018

Full UPF3B function is critical for neuronal differentiation of neural stem cells, 2018, Molecular Brain 8: 33. Alrahbeni T, Sartor F, Anderson J, Miedzybrodzka M, McCaig C, Müller B. DOI: 10.1186/s13041-015-0122-1 Link to publication

Jihan Anderson PhD Student - 2018

Mutation of genes controlling mRNA metabolism and protein synthesis predisposes to neurodevelopmental disorders, 2018, Biochemical Society Transactions 43: 1259-1265. Sartor F, Anderson J, McCaig C, Miedzybrodzka Z, Müller B. DOI: 10.1038/s41598-018-33055-0 Link to publication

Eamon Fitzgerald PhD Student - 2018

Preterm birth and the risk of neurodevelopmental disorders - Is there a role for epigenetic dysregulation?, 2018, Current Genomics 19: 7. Fitzgerald E, Boardman JP, Drake A. DOI: 10.2174/1389202919666171229144807 Link to publication

Hanna Buist PhD Student - 2018

The potential of a novel class of EPAC-selective agonists to combat cardiovascular inflammation, 2018, Journal of Cardiovascular Development and Disease 4: 4: 22. Barker G, Parnell E, Buist H, Adams DR, Yarwood S. DOI: 10.3390/jcdd4040022 Link to publication

Raphae Barlas Vacation Scholar - 2018

Effect of antiplatelet therapy (Aspirin + Dipyridamole versus Clopidogrel) on mortality outcome in ischemic stroke, 2018, American Journal of Cardiology 122: 6: 1085–1090. Barlas RS, Loke YK, Mamas MA, Bettencourt-Silva JH, Ford I, Clark AB, Bowles KM, Metcalf AK, Potter JF, Myint PK. DOI: 10.1016/j.amjcard.2018.05.043 Link to publication

Emma Foster Vacation Scholar - 2018

Long-term facotors associated with fall ad fractures poststroke, 2018, Frontiers in Neurology 9: 210. Foster EJ, Barlas RS, Bettencourt-Silva JH, Clark AB, Metcalf AK, Bowles KM, Potter JF, Myint PK. DOI: 10.3389/fneur.2018.00210 Link to publication

Brian Morton PhD Student - 2017

The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis, 2017, Journal of Allergy and Clinical Immunology 139: 1946–1956. Kurowska-Stolarska M, Hasoo MK, Welsh DJ, Stewart L, McIntyre D, Morton BE, Johnstone S, Miller AM, Asquith DL, Millar NL, Millar AB, Feghali-Bostwick CA, Hirani N, Crick PJ, Wang Y, Griffiths WJ, McInnes IB, McSharry C. DOI: 10.1016/j.jaci.2016.09.021 Link to publication

Sumanth Iyer PhD Student - 2017

A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity, 2017, Nature Scientific Reports 7: 3598. Iyer RS, Chatham L, Sleigh R, Meek DW (2017) DOI: 10.1038/s41598-017-03775-w Link to publication

Elizabeth Hay PhD Student - 2017

Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation., 2017, Neuropeptides 64: 19-25. Hay EA, Knowles C, Kolb A, MacKenzie A. DOI: 10.1016/j.npep.2016.11.010 Link to publication

Elizabeth Hay PhD Student - 2017

Determining Epigenetic targets; a beginner’s guide to identifying genome functionality through database analysis, 2017, In Methods in Molecular Biology (Population Epigenetics) 1589: 29-45. Hay EA, Cowie P, MacKenzie A. Link to publication

Elizabeth Hay PhD Student - 2017

An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome, 2017, Neuropeptides 64: 101-107. Hay EA, Khalaf AR, Marini P, Brown A, Heath K, Sheppard D, MacKenzie A. DOI: 10.1016/j.npep.2016.11.003. Link to publication

Nikki Sloan PhD Student - 2017

Late stage iodination of biologically active agents using a one-pot process from aryl amines, 2017, Chemical Communications 7: 86: 54881-54891. Sloan N, Luthra SK, McRobbie G, Pimlott SL, Sutherland A. DOI: 10.1039/C7RA11860K Link to publication

Nikki Sloan PhD Student - 2017

A one-pot radioiodination of aryl amines via stable diazonium salts: preparation of 125I-Imaging Agents, 2017, Chemical Communications 53: 80:11008-11011. Sloan N, Luthra SK, McRobbie G, Pimlott SL, Sutherland A. DOI: 10.1039/c7cc06211g Link to publication

Dirk-Jan Cornelissen PhD Student - 2017

Current developments in 3D bioprinting for tissue engineering, 2017, Current Opinion in Biomedical Engineering 2: 76-82. Cornelissen D-J. Faulkner-Jones A, Shu W. DOI: 10.1016/j.cobme.2017.05.004 Link to publication

Johannes Brennecke PhD Student - 2017

High yield extraction of E. coli RNA from human whole blood, 2017, Journal of Medical Microbiology 66: 301-311. Brennecke J, Kraut S, Zwadlo K, Gandi SK, Pritchard D, Templeton K, Bachmann T. DOI: 10.1099/jmm.0.000439. Link to publication

Lois Paton PhD Student - 2017

Novel IgG-degrading enzymes of the IgdE protease family link substrate specificity to host tropism of Streptococcus species, 2017, PLoS ONE 12(1). Spoerry C, Hessle P, Lewis MJ, Paton L, Woof JM, von Pawel-Rammingen U DOI: 10.1371/journal.pone.0164809 Link to publication

Dirk-Jan Cornelissen PhD Student - 2016

Coculturing Human Islets with Proangiogenic Support Cells to Improve Islet Revascularization at the Subcutaneous Transplantation Site, 2016, Tissue Eng Part A, 22 (3-4), p 375-85. Buitinga M, Janeczek Portalska K, Cornelissen DJ, Plass J, Hanegraaf M, Carlotti F, de Koning E, Engelse M, van Blitterswijk C, Karperien M, van Apeldoorn A, de Boer J DOI: 10.1089/ten.tea.2015.0317 Link to publication

Sara Hosseinzadah PhD Student - 2016

The multifaceted role of astrocytes in regulating myelination, 2016, Exp Neurol 283: Pt B: 541-9. Kıray H, Lindsay SL, Hosseinzadeh S, Barnett SC DOI: 10.1016/j.expneurol.2016.03.009 Link to publication

Nikki Sloan PhD Student - 2016

Recent Advances in Transition-Metal-Catalyzed Iodination of Arenes, 2016, Synthesis 48: 18: 2969-2980. Sloan N, Sutherland A. DOI: 10.1055/s-0035-1562439 Link to publication

Lois Paton PhD Student - 2016

Novel IgG-degrading enzymes of the IgdE protease family link substrate specificity to host tropism of Streptococcus species, 2016, PLoS ONE 11 and 12(1) correction. Spoerry C, Hessle P, Lewis MJ, Paton L, Woof JM, von Pawel-Rammingen U. DOI: 10.1371/journal.pone.0164809 Link to publication

Dirk-Jan Cornelissen PhD Student - 2015

Bioprinting of human pluripotent stem cells and their directed differentiation into hepatocyte-like cells for the generation of mini-livers in 3D, 2015, Biofabrication 7: 4. Faulkner-Jones A, Catherine Fyfe, Cornelissen D-J, Gardner J, King J, Courtney A, Shu W. DOI: 10.1088/1758-5090/7/4/044102 Link to publication

Chrysi Xintaropoulou PhD Student - 2015

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models, 2015, Oncotarget 6: 25677-25695. Xintaropoulou C, Ward C, Wise A, Marston H, Turnbull A, Langdon SP. DOI: 10.18632/oncotarget.4499 Link to publication

Emma Joseph PhD Student - 2015

Clinical response biomarkers in ovarian cancer: current challenges and future directions, 2015, Clinical Laboratory International, June. Joseph EL, Ferguson MJ, Smith G. DOI: 2015 Apr/May: 12-16. Link to publication

Elizabeth Hay PhD Student - 2015

The noncoding human genome and the future of personalised medicine, 2015, Expert Reviews in Molecular Medicine 17: e4. Cowie P, Hay EA, MacKenzie A. DOI: 10.1017/erm.2014.23. Link to publication

Philip Everson Vacation Scholar - 2013

The utility of scoring systems in critically ill cirrhotic patients admitted to a general intensive care unit, 2013, Journal of Critical Care 29: 6:1131. Emerson P, McPeake J, O'Neill A, Gilmour H, Forrest E, Puxty A, Kinsella J, Shaw M. DOI: 10.1016/j.jcrc.2014.06.027 Link to publication