MRS funding – creating excellent science.

You can read about it in these publications.

Rebecca Budgett PhD Student - 2021

Phosphorylation of the M1 muscarinic acetylcholine receptor mediates protection in neurodegenerative disease, 2021, bioRxiv 2021.04.29.440753. Scarpa M, Molloy C, Jenkins L et al. DOI: 1 0.1101/2021.04.29.440753 Link to publication

Weronika Szlachetka Vacation Scholar - 2021

Predicting 10-year stroke mortality: development and validation of a nomogram, 2021, Acta Neurol Belg. Szlachetka WA, Pana TA, Mamas MA, Bettencourt-Silva JH, Metcalf AK, Potter JF, McLernon DJ, Myint PK DOI: 10.1007/s13760-021-01752-9 Link to publication

David Hughes PhD Student - 2021

Models of osteoarthritis: Relevance and new insights, 2021, Calcif Tissue Int 109:243–256. Samvelyan HJ, Hughes D, Stevens C, Staines KA. DOI: 10.1007/s00223-020-00670-x Link to publication

Adam Bond PhD Student - 2021

Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity, 2021, ChemRxiv. Cambridge: Cambridge Open Engage; This content is a preprint and has not been peer-reviewed. Klein V, Bond AG, Craigon C, Lokey SR, Ciulli A. DOI: 10.33774/chemrxiv-2021-47tqn Link to publication

Deborah Reid PhD Student - 2021

Pharmaceuticals in wastewater treatment plants: A systematic review on the substances of greatest concern responsible for the development of antimicrobial resistance, 2021, Appliced Sciences 11, 6670. . Frascaroli G, Reid D, Hunter C, Roberts J, Helwig K, Spencer J, Escudero A. DOI: 10.3390/app11156670 Link to publication

Dong Xiao PhD Student - 2021

On synthetic instrument response functions of time-correlated single-photon counting based fluorescence lifetime imaging analysis, 2021, Frontiers in Physics, 9, [635645]. Xiao D, Sapermsap N, Safar M, Cunningham MR, Chen Y, and Li D D-U. DOI: 10.3389/fphy.2021.635645 Link to publication

Dong Xiao PhD Student - 2021

Dynamic fluorescence lifetime sensing with CMOS single-photon avalanche diode arrays and deep learning processors, 2021, Biomed Optics Express, 12(6), 3450-3462. Xiao D, Zang Z, Sapermsap N, Wang, Q Xie, W, Chen Y and Li DD-U. DOI: 10.1364/BOE.425663 Link to publication

Shun Qi Yong Vacation Scholar - 2021

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients, 2021, Epigenetics and Chromatin 14:31. Fitzgerald E, Sinton MC, Wernig-Zorc S, Morton NM, Holmes MC, Boardman JP, Drake AJ. DOI: 10.1002/14651858.CD013307.pub2 Link to publication

Eamon Fitzgerald PhD Student - 2021

Altered hypothalamic DNA methylation and stress-induced hyperactivity following early life stress, 2021, Epigenetics and Chromatin 14:31. Fitzgerald E, Sinton MC, Wernig-Zorc S, Morton NM, Holmes MC, Boardman JP, Drake AJ. DOI: 10.1186/s13072-021-00405-8 Link to publication

Ieva Keraite PhD Student - 2021

Correction: Versatile hybrid acoustic micromixer with demonstration of circulating cell-free DNA extraction from sub-ml plasma samples, 2021, Lab on a Chip, Correction of 20, 741-748. Conde A, Keraite I, Ongaro AE, Kersaudy-Kerhoas M. DOI: 10.1039/D1LC90069B Link to publication

Phui Yuen Wong Vacation Scholar - 2021

FMALE score: Combining practical risk scales to improve preoperative predictive accuracy in emergency general surgery: A multi-centre prospective cohort study, 2021, Am J Surgery, 26 April. Wong PY, Ablett AD, Myint PK, Carter B, McCarthy K, Stechman M, Pearce L, Hewitt J. DOI: 10.1016/j.amjsurg.2021.04.009 Link to publication

Eamon Fitzgerald PhD Student - 2021

On synthetic instrument response functions of time-correlated single-photon counting based fluorescence lifetime imaging analysis, 2021, Frontier in Physics, 02 March. Xiao D, Sapermsap N, Safar M, Cunningham M, Chen Y, Li D. DOI: 10.3389/fphy.2021.635645 Link to publication

Eamon Fitzgerald PhD Student - 2021

Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2, 2021, Sci Reports 11(1):9092. Fitzgerald E, Roberts J, Tennant DA, Boardman JP, Drake AJ. DOI: 10.1038/s41598-021-88757-9 Link to publication

Sam Benson PhD Student - 2021

Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo, 2021, Nat Commun 12, 2369. Benson S, de Moliner F, Fernandez A. et al. DOI: 10.1038/s41467-021-22578-2 Link to publication

Ines Nearchou PhD Student - 2021

Automated Detection and Classification of Desmoplastic Reaction at the Colorectal Tumour Front Using Deep Learning, 2021, Cancers, 13, 1615. Nearchou IP, Ueno H, Kajiwara Y, Lillard K, Mochizuki S, Takeuchi K, Harrison DJ, Caie PD. DOI: 10.3390/cancers13071615 Link to publication

Emma Yates Vacation Scholar - 2021

Electromyographic assessment of the lower leg muscles during concentric and eccentric phases of standing heel raise, 2021, Brain, Behaviour and Immunity - Health Volume 13, May, 100219. Fitzgerald E, Boardman JP, Drake AJ. DOI: 10.3390/healthcare9040465 Link to publication

Eamon Fitzgerald PhD Student - 2021

Early life stress and LPS interact to modify the mouse cortical transcriptome in the neonatal period, 2021, Open Forum Infect Dis. Feb; 8(2): ofaa640. Fitzgerald E, Boardman JP, Drake AJ. DOI: 10.1016/j.bbih.2021.100219 Link to publication

Dr David Dorward Principal Investigator - 2021

Histological Evidence of Pulmonary Microthrombosis and Vasculitis in Life-Threatening Respiratory Virus Diseases, 2021, Open Forum Infect Dis. Feb; 8(2): ofaa640. Dolby HW, Potey P, Wilder-Smith AB, Clohisey S, Millar JE, Baillie JK, Dorward DA, Lucas CD, Russell CD. DOI: 10.1093/ofid/ofaa640 Link to publication

Simeon Skopalik PhD Student - 2021

Image‐based computational fluid dynamics for estimating pressure drop and fractional flow reserve across iliac artery stenosis: A comparison with in‐vivo measurements, 2021, Int J Numer Method Biomed Eng. Jan 15; e34. Skopalik S, Barrientos PH, Matthews J, Radjenovic A, Mark P, Roditi G, Paul MC.27. DOI: 10.1002/cnm.3437 Link to publication

Ines Nearchou PhD Student - 2021

A comparison of methods for studying the tumor microenvironment’s spatial heterogeneity in digital pathology specimens, 2021, J Pathol Inform 12:6. Nearchou IP, Soutar A, Ueno H, Harrison DJ, Arandjelovic O, Caie PD. DOI: 10.4103/jpi.jpi_26_0 Link to publication

Dr David Dorward Principal Investigator - 2021

Tissue-Specific Immunopathology in Fatal COVID-19, 2021, Am J Respir Crit Care Med Jan 15;203(2):192-201. Dorward DA, Russell CD, Um IH et al. DOI: 10.1164/rccm.202008-3265OC Link to publication

Dr Alasdair Fraser Principal Investigator - 2021

Rapid GMP-compliant expansion of SARS-CoV-2-specific T cells from convalescent donors for use as an allogeneic cell therapy for Covid-19, 2021, Frontiers in Immunology Jan. Cooper R, Fraser AR, Smith L, Burgoyne P, Imlach SN, Jarvis LM, Turner DM, Zahra S, Turner ML, Campbell JDM. DOI: 10.3389/fimmu.2020.598402 Link to publication

Dong Xiao PhD Student - 2021

One-dimensional deep learning architecture for fast fluorescence lifetime imaging, 2021, IEEE Journal of Selected Topics in Quantum Electronics 27 (4). Xiao D, Chen Y, Li D. DOI: 10.1109/JSTQE.2021.3049349 Link to publication

Marie Bluntzer PhD Student - 2021

Designing stapled peptides to inhibit protein-protein interactions: An analysis of successes in a rapidly changing field, 2021, Peptide Science 113:e24191. Bluntzer MTJ, O'Connell J, Baker TS, Michel J, Hulme AN. DOI: 10.1002/pep2.24191 Link to publication

Roopam Gupta PhD Student - 2020

Deep learning enabled laser speckle wavemeter with a high dynamic range., 2020, Laser & Photonics Reviews 14, 9, 2000120. Gupta R, Bruce GD, Powis SJ, Dholakia K. DOI: 10.1002/lpor.202000120 Link to publication

Elizabeth Hay PhD Student - 2020

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake, 2020, Mol Psychiatry. DOI: 10.1038/s41380-020-0707-7 Link to publication

Roopam Gupta PhD Student - 2020

Extended Kalman filtering projection method to reduce the 3σ noise value of optical biosensors, 2020, ACS Sensors 5, 11, 3474–3482. Li K, Gupta R, Drayton A, Barth I, Conteduca D, Reardon C, Dholakia K and Krauss TF. DOI: 10.1021/acssensors.0c01484 Link to publication

Emma Yates Vacation Scholar - 2020

A novel simplified biomechanical assessment of the heel pad during foot plantarflexion, 2020, Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 235(2), 197-207 Ugbolue UC, Yates EL, Rowland KE, Wearing SC, Gu Y, Lam W-K, Baker JS, Sculthorpe NF & Dutheil F. DOI: 10.1177/0954411920971069 Link to publication

Stylianos Sarrigiannidis PhD Student - 2020

Chiral Tartaric Acid Improves Fracture Toughness of Bioactive Brushite–Collagen Bone Cements, 2020, CS Applied Bio Materials 3 (8), 5056-5066. Sarrigiannidis SO, Moussa H, Dobre O, Dalby MJ, Tamimi F, Salmeron-Sanchez M. DOI: 10.1021/acsabm.0c00555 Link to publication

Olivia Matthews PhD Student - 2020

Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 inrenal tubular cells, 2020, EBioMedicine 62, 103092. Matthews O, Morrison EE, Tranter JD, Starkey Lewis P et al. DOI: 10.1016/j.ebiom.2020.103092 Link to publication

Sven Lange PhD Student - 2020

Dimeric structure of IRAK3 pseudokinase suggests an allosteric mechanism of negative regulation, 2020, Structure 29, 1-19. Lange SM, Nelen MI, Cohen P, Kulathu Y. DOI: 10.1016/j.str.2020.11.004 Link to publication

Eamon Fitzgerald PhD Student - 2020

Maternal influences on fetal brain development: The role of nutrition, infection and stress, and the potential for intergenerational consequences, 2020, Early Human Development 150, 105190. Fitzgerald E, Hor K, Amanda J. Drake A. DOI: 10.1016/j.earlhumdev.2020.105190 Link to publication

Louise Nugent Vacation Scholar - 2020

Cx31.1 expression is modulated in HaCaT cells exposed to UV-induced damage and scrape-wounding, 2020, Journal of Cellular Physiology Vol 236 (2), 911-920. Nugent L, Ofori-Frimpong B, Martin PE, Green CR, Wright CS. DOI: 10.1002/jcp.29901 Link to publication

Despoina Kesidou PhD Student - 2020

Extracellular Vesicle the Promotion of Cardiac Neovascularisation, 2020, Frontiers in Physiol. Sep, Vol 11. Kesidou D, da Costa Martins PA, de Windt LJ, Brittan M, Beqqali A and Baker AH. DOI: 10.3389/fphys.2020.579892 Link to publication

Saphia Matthew PhD Student - 2020

Silk Nanoparticle Manufacture in Semi-Batch Format, 2020, ACS Biomater Sci Eng, 3 Nov. Matthew SAL, Totten JD, Phuagkhaopong S, Egan G, Witte K, Perrie Y, Seib FP. DOI: 10.1021/acsbiomaterials.0c01028.s001 Link to publication

Ieva Keraite PhD Student - 2020

Engineered membranes for residual cell trapping on microfluidic blood plasma separation systems. A comparison between porous and nanofibrous (electrospun) membranes, 2020, BioRxiv:, May. Lopresti F, Keraite I, Ongaro A, Howarth N, La Carrubba V and Kersaudy-Kerhoas M. DOI: 10.1101/2020.05.21.107813 Link to publication

Ieva Keraite PhD Student - 2020

PIK3CA mutation enrichment and quantitation from blood and tissue, 2020, Scientific Reports, 10, 17082. Keraite, I Alvarez-Garcia V, Garcia-Murillas I, Beaney M, Turner NC, Bartos C, Oikonomidou O, Kersaudy-Kerhoas M, Leslie NR. DOI: 10.1038/s41598-020-74086-w. Link to publication

Ieva Keraite PhD Student - 2020

Versatile hybrid acoustic micromixer with demonstration of circulating cell-free DNA extraction from sub-ml plasma samples, 2020, Lab on a Chip, 20, 741-748. Conde A, Keraite I, Ongaro AE, Kersaudy-Kerhoas M. DOI: 10.1039/c9lc01130g Link to publication

Aryan Kaveh PhD Student - 2020

Live Imaging of Heart Injury in Larval Zebrafish Reveals a Multi-Stage Model of Neutrophil and Macrophage Migration, 2020, Frontiers in Cell and Developmental Biology, 8 (579943). Kaveh A, Bruton F, Buckley C, Oremek M, Tucker C, Mullins J, Taylor J, Rossi A. and Denvir M. DOI: 10.3389/fcell.2020.579943 Link to publication

Lorna Hayden PhD Student - 2020

Lipid-specific IgMs induce antiviral responses in the CNS: implications for progressive multifocal leukoencephalopathy in multiple sclerosis, 2020, Acta Neuropathologica Communications, 8 (135). Hayden L, Semenoff T, Schultz V, Merz SF, Chapple KJ, Rodriguez M, Warrington AE, Shi X, McKimmie CS, Edgar JM, Thümmler K, Linington C, and Pingen M. DOI: 10.1186/s40478-020-01011-7 Link to publication

Alasdair Morgan PhD Student - 2020

4D flow MRI for non-invasivemeasurement of blood flow inthe brain: A systematic review, 2020, Journal for Cerebral Blood Flow and Metabolism, 0 (0), 1-13. Morgan A, Thrppleton MJ, Wardlaw JM, Marshall I. DOI: 10.1177/0271678X20952014 Link to publication

Paula Grill Vacation Scholar - 2020

The burden of psychotropic and anticholinergic medicines use in care homes: population-based analysis in 147 care homes, 2020, Age and Ageing, 1-7. Grill P, Marwick C, De Souza N, Burton JK, Hughes C, Guthrie B. DOI: 10.1093/ageing/afaa122 Link to publication

Emma Yates Vacation Scholar - 2020

Sex differences in heel pad stiffness during in-vivo loading and unloading, 2020, Journal of Anatomy, 237(3), 520-528. Ugbolue UC, Yates EL, Wearing SC, Gu Y, Lam W-K, Valentin S, Baker JS, Dutheil F, Sculthorpe NF. DOI: DOI: 10.1111/joa.13207 Link to publication

Daniel Baillache PhD Student - 2020

Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold, 2020, RSC Medicinal Chemistry, 8 September. Baillache DJ, Unciti-Broceta, A. DOI: 10.1039/D0MD00227E Link to publication

Ines Nearchou PhD Student - 2020

Prognostic significance of mesothelin expression in colorectal cancer disclosed by area-specific four-point tissue microarrays, 2020, Virchows Arch 477, 409–420. Shiraishi, T., Shinto, E., Nearchou, I.P., Tsuda H., Kajiwara Y., Einama T., Caie P.D., Kishi Y. and Ueno H. DOI: 10.1007/s00428-020-02775-y Link to publication

Adam Bond PhD Student - 2020

Stereoselective Synthesis of Allele-Specific BET Inhibitors, 2020, Org Biomol Chem 18, 7535. Bond A, Testa A, Ciulli A. DOI: 10.1039/d0ob01165g Link to publication

Ines Nearchou PhD Student - 2020

Spatial immune profiling of the colorectal tumor microenvironment predicts good outcome in stage II patients, 2020, npj Digit. Med. 3, 71. Nearchou IP, Gwyther BM, Georgiakakis ECT, Gavriel CG, Lillard K, Kajiwara Y, Ueno H, Harrison DJ, Caie PD. DOI: 10.1038/s41746-020-0275-x Link to publication

Faidon Kyriakou PhD Student - 2020

Efficiently simulating an endograft deployment: A methodology for detailed CFD analyses, 2020, Annals of Biomedical Engineering. Kyriakou F, Maclean C. DOI: 10.1115/IPACK2019-6395 Link to publication

Faidon Kyriakou PhD Student - 2020

Analysing the cross-section of the abdominal aortic aneurysm neck and its effects on stent deployment, 2020, Nature Scientific Reports, 10, Article Number 4673. Kyriakou F, Dempster W and Nash D. DOI: 10.1038/s41598-019-53820-z Link to publication

Mollie McFarlane PhD Student - 2020

Characterisation of a deep-ultraviolet light-emitting diode emission pattern via fluorescence, 2020, Measurement Science and Technology 31(7): 077001. McFarlane M and McConnell G. DOI: 10.1088/1361-6501/ab78c1 Link to publication

Sarah McGrath PhD Student - 2020

Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis, 2020, Cardiovascular Research Mar 1;116(3):721-735. Rios FJ, Zou ZG, Harvey AP, Harvey KY, Nosalski R, Anyfanti P, Camargo LL, Lacchini S, Ryazanov AG, Ryazanova L, McGrath S, Guzik TJ, Goodyear CS, Montezano AC, Touyz RM. DOI: 10.1093/cvr/cvz164 Link to publication

Jinzhang He Vacation Scholar - 2020

Exclusion rates in randomized controlled trials of treatments for physical conditions: a systematic review, 2020, Trials 21, 228. He J, Morales DR & Guthrie B. DOI: 10.1038/s41582-020-0311-0 Link to publication

George McCanney PhD Student - 2020

Multi- target approaches to CNS repair: Olfactory mucosal­derived mesenchymal stromal cells and heparan sulphate proteoglycans, 2020, Nature Rev Neural, 25 Feb. Lindsay SL. McCanney GA, Willison AG, Barnett SC. DOI: 10.1038/s41582-020-0311-0 Link to publication

Daniel Baillache PhD Student - 2020

Pyrazolopyrimidine Library Screening in Glioma Cells Discovers Highly Potent Antiproliferative Leads That Target the PI3K/mTOR Pathway, 2020, Bioorganic and Medicinal Chemistry, 28 (1), 115214. Valero T, Baillache DJ, Fraser C, Myers SH, Unciti-Broceta, A. DOI: 10.1016/j.bmc.2019.115215 Link to publication

Ilaria Epifano PhD Student - 2019

Host Vesicle Fusion Protein VAPB Contributes to the Nuclear Egress Stage of Herpes Simplex Virus Type-1 (HSV-1) Replication, 2019, Cells 8(2), 120. Saiz-Ros N, Czapiewski R, Epifano I, et al. DOI: 10.3390/cells8020120 Link to publication

Julian Schwartze PhD Student - 2019

TGFβ signaling via ALK1 and ALK5 regulates distinct functional pathways in vein graft intimal hyperplasia, 2019, BioRxiv. Low EL, Schwartze JT, Kelly DJ, Shaw AS, Thorikay M, McClure J, McBride M, Arias-Rivas S, Francis SE, Morrell NW, Delles C, Havenga MJ, Nicklin SA, Ten Dijke P, Baker AH, Bradshaw AC. DOI: 10.1101/860320v1 Link to publication

Faidon Kyriakou PhD Student - 2019

A methodology to quantify the geometrical complexity of the abdominal aortic aneurysm, 2019, Kyriakou F, Dempster W andNash D. Nature Scientific Reports, 9, Article Number 17379. DOI: 10.1038/s41598-019-53820-z Link to publication

Caroline Busch PhD Student - 2019

Bone marrow niche crosses paths with BMPs: a road to protection and persistence in CML, 2019, Biochem Soc Trans 47 (5): 1307–1325. Busch C and Wheadon H. DOI: 10.1042/BST2019022 Link to publication

George McCanney PhD Student - 2019

The Use of Myelinating Cultures as a Screen of Glycomolecules for CNS Repair, 2019, Biology (Basel) 8(3). McCanney GA, Lindsay SL, McGrath MA, Willison HJ, Moss C, Bavington C, Barnett SC. DOI: 10.3390/biology8030052 Link to publication

George McCanney PhD Student - 2019

MyelinJ: an ImageJ macro for high throughput analysis of myelinating cultures., 2019, Bioinformatics. 35(21):4528-4530. Whitehead MJ, McCanney GA, Willison HJ, Barnett SC. DOI: 10.1093/bioinformatics/btz403 Link to publication

Roopam Gupta PhD Student - 2019

Deep learning enabled laser speckle wavemeter with a high dynamic range, 2019, arXiv:1910.10702 [physics.optics]. Gupta R, Bruce G, Powis S, Dholakia K. Link to publication

James O'Sullivan PhD Student - 2019

Refining the Mouse Subtotal Nephrectomy in Male 129S2/SV Mice for Consistent Modeling of Progressive Kidney Disease With Renal Inflammation and Cardiac Dysfunction, 2019, Frontiers in Physiology, 10, 1365. O'Sullivan J et al. DOI: 10.3389/fphys.2019.01365 Link to publication

Julian Schwartze PhD Student - 2019

TGF-β in Vascular Pathobiology, 2019, Schwartze J. Chapter in the “Textbook of Vascular Medicine". Springer Nature Switzerland AG. Touyz R, Delle C (Eds) DOI: 10.1007/978-3-030-16481-2_13 Link to publication

Aryan Kaveh PhD Student - 2019

Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart, 2019, Nature Communications 10(1):5173. Taylor JM, Nelson CJ, Bruton FA, Kaveh A, Buckley C, Tucker CS, Rossi AG, Mullins JJ, Denvir MA. DOI: 10.1038/s41467-019-13112-6 Link to publication

Faidon Kyriakou PhD Student - 2019

Evaluation of a new approach for modelling full ring stent bundles with the inclusion of manufacturing strains, 2019, Annals of Biomedical Engineering p13. Kyriakou F, Bow D, Dempster W, Brodie R & Nash D. DOI: 10.1007/s10439-019-02322-0 Link to publication

Elizabeth Hay PhD Student - 2019

Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid-1 receptor gene promoter; implications for cannabinoid pharmacogenetics, 2019, Hum Mutat Oct 14. Hay EA, Cowie P, McEwan AR, Ross R, Pertwee RG, MacKenzie A. DOI: 10.1002/humu.23931 Link to publication

Elizabeth Hay PhD Student - 2019

Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour, 2019, Psychoneuroendocrinology 109:104407. Hay EA, McEwan A, Wilson D, Barrett P, D'Agostino G, Pertwee RG, MacKenzie A. DOI: 10.1016/j.psyneuen.2019.104407 Link to publication

Kym Bain PhD Student - 2019

Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity, 2019, Br J Dermatol. Apr 13. Bain KA, McDonald E, Moffat F, Tutino, M, Castelino M, Barton A, Cavanagh J, Ijaz UZ, Siebert S, McInnes IB, Astrand A, Holmes S, Milling SWF. DOI: 10.1111/bjd.18008 Link to publication

Sam Benson PhD Student - 2019

SCOTfluors: small, conjugatable, orthogonal and tunable fluorophores for in vivo imaging of cell metabolism, 2019, Angew Chem Int Ed 58, 6911-6915. Benson S, Frnandez A, Barth N et al. DOI: 10.1002/anie.201900465 Link to publication

Ines Nearchou PhD Student - 2019

Novel Internationally Verified Method Reports Desmoplastic Reaction as the Most Significant Prognostic Feature For Disease-specific Survival in Stage II Colorectal Cancer, 2019, American Journal of Surgical Pathology, 43(9):1239-1248. Nearchou IP, Kajiwara Y, Mochizuki S, Harrison D, Caie P, Ueno H. DOI: 10.1097/PAS.0000000000001304 Link to publication

Tiberiu Pana Vacation Scholar - 2019

Individual and Combined Impact of Heart Failure and Atrial Fibrillation on Ischemic Stroke Outcomes A Prospective Hospital Register Cohort Study, 2019, Stroke Vol 50, No 7. Pama TA, McLernon DJ, Mamas MA, Bettencourt-Silva JH, Metcalf AK, Potter JF, Myint PK. DOI: 10.1161/STROKEAHA.119.025481 Link to publication

George McCanney PhD Student - 2019

Low sulfated heparins target multiple proteins for central nervous system repair, 2019, Glia, 67, 4, pp668-687. McCanney GA, McGrath MA, Otto TD, Burchmore R, Yates EA, Bavington CD, Willison HJ, Turnbull JE, Barnett SC. DOI: doi.org/10.1002/glia.23562 Link to publication

Kirstyn Gardner Vacation Scholar - 2019

Cortical thickness, white matter hyperintensities, and cognition after stroke, 2019, International Journal of Stroke, April. Dickie DA, Gardner K, Wagener A, Wyss A, Arba F, Wardlaw JM, Dawson J. DOI: doi.org/10.1177/1747493019851291 Link to publication

Elizabeth Hay PhD Student - 2019

Genetic and pharmacological influences modulating tissue specific regulation of the cannabinoid receptor-1 gene promoter implications for cannabinoid pharmacogenetics, 2019, BioRxiv. Hay E, Cowie P, McEwan A, Wilson D, Ross R, Barrett P, Pertwee RG, MacKenzie A. DOI: doi.org/10.1101/544585 Link to publication

Elizabeth Hay PhD Student - 2019

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests its role in anxiety and male alcohol intake, 2019, BioRxiv. McEwan A, Hay E, Davidson C, Turnbull Y, Marini P, Wilson D, McIntosh A, Adams MJ, Murgatroyd C, Barrett P, Delibegovic M, Clark, T, MacKenzie A. DOI: doi.org/10.1101/572065 Link to publication

Maria Gómez-Herranz PhD Student - 2019

The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis, 2019, Cellular Signalling, Aug, 60, pp39-56. Gómez-Herranz M, Nekulova M, Faktor J, Hernychova L, Kote S, Sinclair EH, Nenutil R, Vojtesek B, Ball KL, Hupp TR. DOI: 10.1016/j.cellsig.2019.03.024 Link to publication

Awa Sarr PhD Student - 2019

Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031, 2019, Scientific Reports, 9, 7643. Sarr A, Bre J, Um I, Chan T, Mullen P, Harrison DJ, Reynolds PA. DOI: 10.1038/s41598-019-44089-3 Link to publication

Ines Nearchou PhD Student - 2019

Automated Analysis of Lymphocytic Infiltration, Tumor Budding, and Their Spatial Relationship Improves Prognostic Accuracy in Colorectal Cancer, 2019, Cancer Immunology Research, 7(4), pp.609-620. Nearchou IP, Lillard K, Gavriel CG, Ueno H, Harrison DJ, Caie PD. DOI: 10.1158/2326-6066.CIR-18-0377 Link to publication

Roopam Gupta PhD Student - 2019

Label-free optical hemogram of granulocytes enhanced by artificial neural networks, 2019, Optics Express 27, 13706-13720. Gupta R, Chen M, Malcolm GPA, Hempler N, Dholakia K, Powis S. DOI: doi.org/10.1364/OE.27.013706 Link to publication

Kyriakos Michail PhD Student - 2019

An in vitro model for studying CNS white matter, 2019, F1000 Research. Bijland S, Thomson G, Euston M, Michail K, Thümmler K, Mücklisch S, Crawford CL, Barnett S, McLaughlin M, Anderson J, Linington C, Brown E, Kalkman ER, Edgar J. DOI: f1000research.com/articles/8-117/v1 Link to publication

George McCanney PhD Student - 2018

Neural cell cultures to study spinal cord injury, 2018, Drug Discovery Today: Disease Models:25-26C;11-20. McCanney GA, Whitehead M, McGrath MA, Lindsay SL, Barnett SC. Link to publication

Elizabeth Hay PhD Student - 2018

Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4, 2018, Nutritional Neuroscience. July. Sergi D, Morris AC, Kahn DE., McLean, FH, Hay EA, Kubitz P, MacKenzie A, Martinoli MG, Drew JE, Williams LM. DOI: 10.1080/1028415X.2018.1501533 Link to publication

Sarah McGrath PhD Student - 2018

Protease-activated receptor-2 in synovial joint pathobiology, 2018, Frontiers in Endocrinology, 9, p.257. McCulloch K, McGrath S, Huesa C, Dunning L, Litherland G, Crilly A, Hultin L, Ferrell WR Lockhart JC, Goodyear CS. DOI: 10.3389/fendo.2018.0025 Link to publication

Caroline Busch PhD Student - 2018

Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal, 2018, Cell Death & Disease. Volume 9, Article number: 927. Toofan P, Busch C, Morrison H, O'Brien S, Jørgensen H, Copland M, Wheadon H. DOI: 10.1038/s41419-018-0905-2 Link to publication

Ieva Keraite PhD Student - 2018

Laser ablation of polylactic acid sheets for the rapid prototyping of sustainable, single-use, disposable medical micro-components, 2018, ACS Sustainable Chemistry & Engineering 6: 4: 4899–4908. Alfredo Edoardo Ongaro, Keraite I, Liga A, Conoscenti G, Coles S, Schulze H, Bachmann TT, Parvez K, Casiraghi C, Howarth NM, La Carrubba V, Kersaudy-Kerhoas M. DOI: 10.1021/acssuschemeng.7b04348 Link to publication

Ieva Keraite PhD Student - 2018

A simple and robust real-time qPCR method for the detection of PIK3CA mutations, 2018, Scientific Reports 8: 4290. Alvarez-Garcia V, Bartos C, Keraite I, Trivedi U, Brennan PM, Kersaudy-Kerhoas M, Gharbi K, Oikonomidou O, Leslie NR. DOI: 10.1038/s41598-018-22473-9 Link to publication

Andrew Ablett Vacation Scholar - 2018

Cognitive impairment is associated with mortality in older adults in the emergency surgical setting: Findings from the Older Persons Surgical Outcomes Collaboration (OPSOC): A prospective cohort study, 2018, Surgery, 165, 5, p978–984 . Ablett A, McCarthy K, Carter B, Pearce L, Stechman M, Moug M, Hewitt J, Myint PK, Older Persons Surgical Outcomes Collaboration DOI: 10.1016/j.surg.2018.10.013 Link to publication

Theresa Mulholland PhD Student - 2018

Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient, 2018, Nature Scientific Reports 8: 14672. Mulholland T, McAllister M. DOI: 10.1038/s41598-018-33055-0 Link to publication

Jihan Anderson PhD Student - 2018

Full UPF3B function is critical for neuronal differentiation of neural stem cells, 2018, Molecular Brain 8: 33. Alrahbeni T, Sartor F, Anderson J, Miedzybrodzka M, McCaig C, Müller B. DOI: 10.1186/s13041-015-0122-1 Link to publication

Jihan Anderson PhD Student - 2018

Mutation of genes controlling mRNA metabolism and protein synthesis predisposes to neurodevelopmental disorders, 2018, Biochemical Society Transactions 43: 1259-1265. Sartor F, Anderson J, McCaig C, Miedzybrodzka Z, Müller B. DOI: 10.1038/s41598-018-33055-0 Link to publication

Eamon Fitzgerald PhD Student - 2018

Preterm birth and the risk of neurodevelopmental disorders - Is there a role for epigenetic dysregulation?, 2018, Current Genomics 19: 7. Fitzgerald E, Boardman JP, Drake A. DOI: 10.2174/1389202919666171229144807 Link to publication

Hanna Buist PhD Student - 2017

The potential of a novel class of EPAC-selective agonists to combat cardiovascular inflammation, 2017, Journal of Cardiovascular Development and Disease 4: 4: 22. Barker G, Parnell E, Buist H, Adams DR, Yarwood S. DOI: 10.3390/jcdd4040022 Link to publication

Raphae Barlas Vacation Scholar - 2018

Effect of antiplatelet therapy (Aspirin + Dipyridamole versus Clopidogrel) on mortality outcome in ischemic stroke, 2018, American Journal of Cardiology 122: 6: 1085–1090. Barlas RS, Loke YK, Mamas MA, Bettencourt-Silva JH, Ford I, Clark AB, Bowles KM, Metcalf AK, Potter JF, Myint PK. DOI: 10.1016/j.amjcard.2018.05.043 Link to publication

Emma Foster Vacation Scholar - 2018

Long-term facotors associated with fall ad fractures poststroke, 2018, Frontiers in Neurology 9: 210. Foster EJ, Barlas RS, Bettencourt-Silva JH, Clark AB, Metcalf AK, Bowles KM, Potter JF, Myint PK. DOI: 10.3389/fneur.2018.00210 Link to publication

Brian Morton PhD Student - 2017

The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis, 2017, Journal of Allergy and Clinical Immunology 139: 1946–1956. Kurowska-Stolarska M, Hasoo MK, Welsh DJ, Stewart L, McIntyre D, Morton BE, Johnstone S, Miller AM, Asquith DL, Millar NL, Millar AB, Feghali-Bostwick CA, Hirani N, Crick PJ, Wang Y, Griffiths WJ, McInnes IB, McSharry C. DOI: 10.1016/j.jaci.2016.09.021 Link to publication

Sumanth Iyer PhD Student - 2017

A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity, 2017, Nature Scientific Reports 7: 3598. Iyer RS, Chatham L, Sleigh R, Meek DW (2017) DOI: 10.1038/s41598-017-03775-w Link to publication

Elizabeth Hay PhD Student - 2017

Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation., 2017, Neuropeptides 64: 19-25. Hay EA, Knowles C, Kolb A, MacKenzie A. DOI: 10.1016/j.npep.2016.11.010 Link to publication

Elizabeth Hay PhD Student - 2017

Determining Epigenetic targets; a beginner’s guide to identifying genome functionality through database analysis, 2017, In Methods in Molecular Biology (Population Epigenetics) 1589: 29-45. Hay EA, Cowie P, MacKenzie A. Link to publication

Elizabeth Hay PhD Student - 2017

An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome, 2017, Neuropeptides 64: 101-107. Hay EA, Khalaf AR, Marini P, Brown A, Heath K, Sheppard D, MacKenzie A. DOI: 10.1016/j.npep.2016.11.003. Link to publication

Nikki Sloan PhD Student - 2017

Late stage iodination of biologically active agents using a one-pot process from aryl amines, 2017, Chemical Communications 7: 86: 54881-54891. Sloan N, Luthra SK, McRobbie G, Pimlott SL, Sutherland A. DOI: 10.1039/C7RA11860K Link to publication

Nikki Sloan PhD Student - 2017

A one-pot radioiodination of aryl amines via stable diazonium salts: preparation of 125I-Imaging Agents, 2017, Chemical Communications 53: 80:11008-11011. Sloan N, Luthra SK, McRobbie G, Pimlott SL, Sutherland A. DOI: 10.1039/c7cc06211g Link to publication

Dirk-Jan Cornelissen PhD Student - 2017

Current developments in 3D bioprinting for tissue engineering, 2017, Current Opinion in Biomedical Engineering 2: 76-82. Cornelissen D-J. Faulkner-Jones A, Shu W. DOI: 10.1016/j.cobme.2017.05.004 Link to publication

Johannes Brennecke PhD Student - 2017

High yield extraction of E. coli RNA from human whole blood, 2017, Journal of Medical Microbiology 66: 301-311. Brennecke J, Kraut S, Zwadlo K, Gandi SK, Pritchard D, Templeton K, Bachmann T. DOI: 10.1099/jmm.0.000439. Link to publication

Lois Paton PhD Student - 2017

Novel IgG-degrading enzymes of the IgdE protease family link substrate specificity to host tropism of Streptococcus species, 2017, PLoS ONE 12(1). Spoerry C, Hessle P, Lewis MJ, Paton L, Woof JM, von Pawel-Rammingen U DOI: 10.1371/journal.pone.0164809 Link to publication

Dirk-Jan Cornelissen PhD Student - 2016

Coculturing Human Islets with Proangiogenic Support Cells to Improve Islet Revascularization at the Subcutaneous Transplantation Site, 2016, Tissue Eng Part A, 22 (3-4), p 375-85. Buitinga M, Janeczek Portalska K, Cornelissen DJ, Plass J, Hanegraaf M, Carlotti F, de Koning E, Engelse M, van Blitterswijk C, Karperien M, van Apeldoorn A, de Boer J DOI: 10.1089/ten.tea.2015.0317 Link to publication

Sara Hosseinzadah PhD Student - 2016

The multifaceted role of astrocytes in regulating myelination, 2016, Exp Neurol 283: Pt B: 541-9. Kıray H, Lindsay SL, Hosseinzadeh S, Barnett SC DOI: 10.1016/j.expneurol.2016.03.009 Link to publication

Nikki Sloan PhD Student - 2016

Recent Advances in Transition-Metal-Catalyzed Iodination of Arenes, 2016, Synthesis 48: 18: 2969-2980. Sloan N, Sutherland A. DOI: 10.1055/s-0035-1562439 Link to publication

Lois Paton PhD Student - 2016

Novel IgG-degrading enzymes of the IgdE protease family link substrate specificity to host tropism of Streptococcus species, 2016, PLoS ONE 11 and 12(1) correction. Spoerry C, Hessle P, Lewis MJ, Paton L, Woof JM, von Pawel-Rammingen U. DOI: 10.1371/journal.pone.0164809 Link to publication

Dirk-Jan Cornelissen PhD Student - 2015

Bioprinting of human pluripotent stem cells and their directed differentiation into hepatocyte-like cells for the generation of mini-livers in 3D, 2015, Biofabrication 7: 4. Faulkner-Jones A, Catherine Fyfe, Cornelissen D-J, Gardner J, King J, Courtney A, Shu W. DOI: 10.1017/erm.2014.23. Link to publication

Philip Everson Vacation Scholar - 2013

The utility of scoring systems in critically ill cirrhotic patients admitted to a general intensive care unit, 2013, Journal of Critical Care 29: 6:1131. Emerson P, McPeake J, O'Neill A, Gilmour H, Forrest E, Puxty A, Kinsella J, Shaw M. DOI: 10.1016/j.jcrc.2014.06.027 Link to publication