Investigating the effect of early-life socioeconomic circumstances on late-life brain health.

Early-life socioeconomic circumstances (elSEC) have profound effects on late-life brain health. Improving its measurement and uncovering its mechanism will inform social health policy and interventions into brain ageing and health. This project will investigate elSEC in volunteers now in their 60s, of whom we hold extensive early life data, including birth, childhood, parental, household, and school information. We will investigate their relationships and decide the most infomative way to quantify this data into a single measure of elSEC. We will then investigate if brain health (as assessed by an MRI brain scan) is affected by their early life environment.