Synthesis of copper-substituted tricalcium phosphate – a potential therapeutic bone cement

There are over 9 million osteoporotic (fragility) bone fractures globally per year. Bone fractures that require surgical intervention to repair can be associated with two significant clinical problems: infection of the fracture site and slow or failed fracture healing. Such fractures are often treated with a calcium phosphate cement that can help the bone to repair. This project will synthesis a new cement composition that contains low levels of copper ions; based on previous studies this copper may provide antibacterial properties and stimulate the formation of new blood vessels, which is an important stage in successful bone fracture repair.